Frank Gore has a hip injury and is questionable to return for the 49ers in Monday night’s game against the Cardinals.

As if losing Vincent Jackson to an injury in his season debut wasn’t enough, the Chargers have now lost perhaps their biggest remaining playmaker — Mike Tolbert – to an injury against the Colts.

In an interesting turn of events, the Chargers announced during the second quarter of Sunday night’s game against the Colts that WR Vincent Jackson is out for the rest of the game with a right calf injury.

A look at the notable injuries from Sunday’s games in Week 12.

The Broncos have been helpless in watching the Rams score 27 unanswered points during the second half Sunday, and to add injury to insult have lost safety Brian Dawkins to a knee injury.

The Ravens are missing some key regulars in their matchup against the Bucs, as FB Le’Ron McClain, LT Michael Oher and SS Dawan Landry have left with injuries.

Bucs starting free safety and special teams standout Cody Grimm was carted off the field at M&T Bank Stadium Sunday with what all indications are a serious left ankle injury.

An undisclosed leg injury has forced Seahawks CB Marcus Trufant out of Sunday’s game against the Chiefs.

Tempers boiled over midway through the fourth quarter, and Texans WR Andre Johnson and Titans CB Cortland Finnegan were ejected.

For those of you who follow the Titans, you’ll want to know that starting C Eugene Amano is done for the day against the Texans.

The injuries continue to pile up between the Vikings and Redskins at FedEx Field.

Adrian Petersonis seeing a heavy workload in interim coach Leslie Frazier’s first game at the helm of the Vikings, but it has to be cause for concern that the running back limped off the field with an apparent right ankle injury at FedEx Field.

The first injury to come across the news desk Sunday is out of Buffalo, where Bills starting DE Dwan Edwards has left the game against the Steelers with a hamstring problem.

The Albert Haynesworth saga took another surprising turn Sunday.

Cowboys RB Marion Barber suffered a calf injury late in Thursday’s game against the Saints.