Star receiver Calvin Johnson’s status is in doubt for the Lions’ home opener against the Chiefs.

With Week 1 nearly in the books, here’s a look at the notable injuries from Sunday’s games.

They were locked out for 136 days, an NFL record for labor stoppage. Now NFL players are ready to get back at it.

Colts WR Reggie Wayne and TE Jacob Tamme — both listed as questionable this week — are active for Thursday night’s matchup with the Titans.

Colts LB Gary Brackett will be active Sunday against the Cowboys after missing the previous three games with a toe injury.

The San Diego Chargers have Antonio Gates back on the field for their showdown against the Indianapolis Colts.

The Colts will start Donald Brown at running back Sunday against the Bengals since Joseph Addai (neck) and Mike Hart (ankle) are inactive.

The Colts and free-agent LB Gary Brackett agreed on a five-year contract Friday, according to a league source. The deal is worth up to $33 million, with $12 million guaranteed.

With the clock about to strike midnight in the East, here’s a look at how some of the top players could begin to come off the market. A handful of players will get new deals tonight, with DE Julius Peppers and LB Karlos Dansby likely in line for the biggest paydays.

The revolving door leading to the Cleveland Browns’ quarterback position may just continue spinning. The Cleveland Plain-Dealer, according a league source with knowledge of the situation, reports that the Browns are in trade talks with more than one team regarding a quarterback.

NFL Network insider Jason La Canfora went Around the League on Friday with NFL Total Access’ Fran Charles and touched on a few interesting notes.

A fourth-down gamble by the Saints late during the second quarter didn’t pay off.

Linebacker Gary Brackett called the Colts’ appearance in Super Bowl XLIV “the ultimate business trip.”

Colts DE Dwight Freeney will be active vs. the Colts after he was expected to miss two weeks with a strained right quadriceps. LB Gary Brackett will be out.

Three Colts defensive starters are questionable to play this weekend against the Seahawks. LB Gary Brackett could miss his second consecutive game with a knee injury. DE Dwight Freeney (quadricep) said Thursday that he remains hopeful that he will be able to play through a strained quadriceps, but that appears to unlikely. CB Kelvin Hayden (hamstring) and DT Keyunta Dawson (foot) also are listed as questionable.