The Giants’ running game has been most effective when using a multiple-back rotation, in which someone can spell bruising Brandon Jacobs. But whether or not the team will have such a luxury come Sunday for its big game against the Cowboys remains in question.

Teams have released their practice participation reports for Wednesday. Here’s what’s happening with some of the notable injuries.

Giants RB Danny Ware suffered a concussion after getting hit late in the third quarter and will not return against the Broncos.

Broncos convert a turnover into seven points.

Giants RB Brandon Jacobs looks like a attractive fantasy option in Week 12.

Giants RB Ahmad Bradshaw is wearing a boot on his left foot after already dealing with a cracked bone in his right foot for the past six weeks.

NFL Network’s Jason La Canfora reports that Giants WR Domenik Hixon (hamstring), DE Chris Canty (calf), CB Aaron Ross (hamstring) and RB Danny Ware (elbow) are all out for Sunday’s matchup with the Chiefs.

The Eagles’ season-opening victory over the Panthers was dampened by the news that QB Donovan McNabb suffered a fractured rib.

The New York Giants have placed their franchise tag on Brandon Jacobs, making it likely that he’ll remain with Big Blue in 2009. He is still free to negotiate with other teams, but the price tag of two first-round picks as compensation almost guarantees his return.