Fox Sports insider and NFL Network contributor Jay Glazer reported earlier Monday that the Rams fired coach Steve Spagnuolo. NFL.com analyst Michael Lombardi reported that general manager Billy Devaney also is out in St. Louis.

Monday could set the stage for significant transition around the NFL, with a laundry list of coaches and general managers resting on the hot seat. NFL Network’s Michael Lombardi and Jason La Canfora visited the “NFL GameDay Morning” set on Sunday to share what they’ve heard about the changes to come.

The names of Titans coach Jeff Fisher and former Steelers coach Bill Cowher are the first to come up on the hot list of candidates to replace coaches on the hot seat.

And now for a few thoughts, observations and highlights as we wrap up Day 2 of the NFL Scouting Combine.

In the aftermath of the non-trade of Vincent Jackson, Rams GM Billy Devaney defended the Chargers for holding firm in their asking price.

The Rams are fielding multiple trade offers for the 33rd overall draft pick, and some proposals include a 2011 first-round selection, league sources confirmed to NFL Network insider Michael Lombardi.

The St. Louis Rams will be the first on the clock at the 2010 NFL Draft for the second straight day Friday, and GM Billy Devaney said that all options are open.

Rams general manager Billy Devaney told NFL Network’s Fran Charles that the front office is unanimous on who the team will take with the No. 1 pick.

Rams general manager Billy Devaney told NFL Network’s Stacey Dales on Wednesday that he met with his staff for three hours and there was almost a consensus on who the team should take at No. 1. Devaney stopped short of telling Dales who that player was, although most people believe it will be Oklahoma QB Sam Bradford.

Saints restricted free agent Pierre Thomas hasn’t made any visits to other teams, and hinted the two sides are working on a deal, according to The Times-Picayne.

The NFL in April has more bluffing than the main event table in the World Series of Poker. Teams generally don’t want to tip their hand too early. So in the wake of reports that St. Louis was interested in Oklahoma QB Sam Bradford, GM Billy Devany went into Phil Hellmuth mode.

Colt McCoy revealed that the Rams are one of six teams with which he’ll hold a private workout. While the Rams do their due diligence with a closer look at McCoy, he could represent an option for them with the No. 33 pick.

No sooner were NFL teams connected to having interest in Donovan McNabb did they start lining up to deny that interest.

League sources told me that several teams are actively pursuing Eagles QB Donovan McNabb. A source with knowledge of the situation said that McNabb was being pursued by “some teams that would surprise you, and some you would expect.”

One of the latest reports to surface late Thursday afternoon is that Oklahoma QB Sam Bradford, the consensus No. 1 pick among draftniks, will hold private workouts for two teams — the Rams and Redskins.