You’re a pretty big deal, Tim Tebow, but — just a question — what you gonna do when the 24-inch pythons run wild on you, brother?

Tune into NFL Network’s “Around the League” Friday at 5 p.m. ET to hear San Francisco 49ers wide receiver Michael Crabtree talk about his team’s hot start and big game Sunday against the upstart Detroit Lions.

The latest entry in the “Stand by Your Embattled Quarterback” movement comes courtesy of Jason Witten.

As we will highlight in our “Tale of the Tape” this week — the Giants versus the Bills — we take particular interest in if and how a defense can get to the quarterback.

True to his prediction, Rex Ryan isn’t backing off his belief the New York Jets are Super Bowl-bound. Not that anyone would expect that.

When the Green Bay Packers decided to sport a throwback look that tossed it all the way back to 1929 — back when teams wore leather helmets and league uniform standards were much different than in today’s game — obviously, there were skeptics.

Shek & Rank welcome Jeff Pearlman, author of “Sweetness: The Enigmatic Life of Walter Payton,” to discuss the feedback he has received for telling the sometimes-dark story of an American legend, plus kibitz about the USFL and condiments.

Joseph Addai’s hamstring will most likely keep him out of action this week, while Curtis Painter has solidified his grip on the starting QB job.

With a win against Dallas on Sunday, New England’s Tom Brady and Bill Belichick can tie Pro Football Hall of Famers Dan Marino and Don Shula of Miami for the most wins (116) by a quarterback-head coach duo in the Super Bowl era (since 1966).

Jason Smith takes his weekly look at fantasy quarterbacks and with Philip Rivers on a bye this week, Jason welcomes a new name into his list of the top five.

With Julio Jones out of action this week, it seems unlikely that the Falcons will rely on just one receiver to take his place.

Few players in the history of football are as universally beloved as the late Chicago Bears running back Walter Payton. Enjoy the legendary skills and grace of the man called “Sweetness” in the premiere of “A Football Life: Walter Payton” Thursday at 10 p.m. ET on NFL Network.

San Francisco 49ers linebacker Patrick Willis joined this week’s Cover Two Podcast and said the team’s 4-1 start stems from a lack of individualism and an understanding that they’re far from a finished product.

In the first hour, Michael Fabiano, Jason Smith and special guest host Adam Rank let you know who to start and who to sit in Week 6, and talk about what you should do if Tim Tebow is available in your league. In the second hour, Dave Dameshek joins the guys to go over which running backs you may want to sit in Week 6 and how you should go about trading players this early in the season.

We enjoyed bantering with you all with our LeBron James conversation. Now, we’ll return the favor by answering a few of your mailbag questions.