Jacobs uncertain for Sunday: After missing practice on Wednesday and Thursday, reports are that Giants running back Brandon Jacobs is dealing with a sprained MCL. There is still a chance that he could practice on Friday, making him a possibility for Sunday’s game against Seattle. If he can’t go, Ahmad Bradshaw has shown that he is capable of carrying a full workload for New York. The Seahawks have been a middle-of-the-road fantasy defense against the run, but the Giants figure to spend most of the afternoon protecting a lead, meaning Big Blue’s running backs should be in for a workout.
Jackson misses another practice: Concern is rising in San Diego after receiver Vincent Jackson missed a second practice on Thursday with a hamstring injury. It’s particularly troubling for a team playing without Antonio Gates and going up against a Denver Broncos defense that is expecting to welcome Champ Bailey back to the field. Without Jackson, Malcom Floyd likely becomes the primary target for Philip Rivers with Patrick Crayton seeing extra snaps. Denver’s secondary has allowed the second-most fantasy points to receivers this year, and even with Bailey returning, it’s not going to get better overnight. Expect San Diego’s aerial assault to be slowed but not shut down.
Pettis to replace Amendola: With Danny Amendola officially finished for the season, the Rams are turning to rookie Austin Pettis as their new slot receiver. Earlier in the season, St. Louis tried fellow rookie Greg Salas at the position, with disappointing results. This season, Pettis has six catches for 40 yards, but with the Rams on a bye this week, he’ll have extra time to figure out his new role. St. Louis’ passing game has sputtered this season, so the former Boise State wideout will have a chance to become an impact player in Josh McDaniels’ offense.
— Marcas Grant