The Eagles lost their offensive leader and defensive leader within minutes of each other in the the second quarter.
Quarterback Kevin Kolb and LB Stewart Bradley are both out after suffering concussions, according to Fox broadcaster Joe Buck.
Kolb was injured while taking a sack from Packers LB Clay Matthews and fumbling the ball out of bounds. The injury was originally thought to be to Kolb’s jaw as trainers were looking at his face on the sidelines.
Kolb returned for one series in the second quarter, but did not return to the sidelines with his teammates to start the second half.
Michael Vick will now take over as the Eagles’ quarterback.
Bradley also left in the second quarter after making his first start since 2008. He missed all of 2009 with a torn ACL.
The injury news tops off a particularly rough first half for the Eagles, who also lost FB Leonard Weaver and C Jamaal Jackson to injuries in the second quarter.