Joe Staley was limited in his third consecutive practice, but he’s listed as questionable, meaning the 49ers’ left tackle might be available Monday night against the Cardinals after missing the previous five games because of a knee injury.

“You just never know with the progress he can show from one day to the next, and he’s done a great job this week, but we’re just going to play it and see how it goes,” said 49ers coach Mike Singletary, who added Saturday that Staley “possibly” could be used as a backup so he doesn’t disrupt the offensive line’s continuity.

Staley, a 2007 first-round draft pick who has started in all 39 NFL games he has played, is listed as the backup on the 49ers’ depth chart. Barry Sims, an 11-year veteran, has started at left tackle in Staley’s absence.

Veteran LB Takeo Spikes (hamstring) also is listed as questionable after returning to practice Saturday following two days of rest. Isaac Bruce (ankle), who didn’t play in the previous two games, is listed as doubtful, but Singletary said the former starting wide receiver is “out.”

The Cardinals listed LB Bert Berry (illness), DE Kenny Iwebema (thumb) and TE Stephen Spach (knee) as questionable. All three either missed a practice or were limited this week.

• Check out NFL.com’s injuries page for the latest reports.

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