Lions: QB Drew Henson (3rd), QB Daunte Culpepper, DB Dexter Wynn, DT Langston Moore, T Jon Dunn, G Manny Ramirez, G Damon Cook, WR Shawn McDonald.
Analysis: Quarterback Dan Orlovsky will start with Culpepper out. Receiver Calvin Johnson is active and is safe to start. RB Kevin Smith is also active and will start.
Colts: SS Bob Sanders, RB Joseph Addai, LB Tyjuan Hagler, LB Gary Brackett, LB Rufus Alexander, DT Eric Foster, WR Pierre Garcon, DT Keyunta Dawson.
Analysis: Colts running back Dominic Rhodes is a solid start against the Lions. Detroit running back Kevin Smith gets a small upgrade as Sanders is good against the run.