The Eagles cut veteran defensive end Jerome McDougle as the team released 12 players to trim down to the 53-player limit.
McDougle, 29, was selected 15th overall in 2003, but has been hampered by injuries during his career. He missed the entire 2007 season after injuring his right triceps in preseason.
The Eagles also released cornerback Kyle Arrington, fullbacks Jed Collins and Jason Davis, receivers Michael Gasperson and Shaheer McBride, defensive tackles Mike Marquardt and Montae Reagor, linebackers Justin Roland and Andy Studebaker, tight end Kris Wilson and guard Scott Young.
The team also placed tackle King Dunlap (ankle) and guard Mike Gibson on the injured-reserve list.